Open-label vs blinded clinical trials and when to trust each one
Some treatments cannot be disguised. This guide explains open-label trials, the biases they risk and how to judge them, using the LATE-MT stroke and SINGLE-AF trials.
30 October 2026
Clinical trials, drug development and research news
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Some treatments cannot be disguised. This guide explains open-label trials, the biases they risk and how to judge them, using the LATE-MT stroke and SINGLE-AF trials.
30 October 2026
Worried about getting a dummy pill in a trial? This guide explains placebos, blinding and your rights, using Norway's NOPARK Parkinson's trial as a worked example.
27 October 2026
Patient GuidesA missed primary endpoint is still evidence. Using the 2026 CARDIO-TTRansform trial, this guide explains neutral results, subgroups, safety and what happens next for patients.
23 October 2026
Patient GuidesA 69% risk cut can mean a handful of people. This guide shows how to read absolute risk, NNT, confidence intervals and p-values using a real 2026 trial.
20 October 2026
Patient GuidesWhere to search, how to read a trial listing, what to ask before you sign and your rights once you join, for patients in the UK, US and EU.
9 October 2026
Approved does not always mean available. This guide explains how the FDA, MHRA and EMA review medicines, how NICE decides NHS funding, and why countries differ.
8 October 2026