Clinical trials, drug development and research news
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CardiologyIn PADN-HF-PH, adding pulmonary artery denervation to standard medicines halved clinical worsening in heart failure patients with raised lung pressure over about a year.
30 August 2026
CardiologyIn the TRIC-I-HF trial, repairing the tricuspid valve through a vein raised the share alive and out of hospital at three years from 21% to 52%.
30 August 2026
CardiologyIn the AIR-STEMI trial, software that measures blood flow from routine angiograms meant fewer stents, fewer complications and fewer repeat heart events than judging by eye.
29 August 2026
CardiologyIn LIBREXIA ACS, milvexian did not reduce heart attacks, strokes or heart deaths after acute coronary syndrome, though it also didn't increase serious bleeding.
29 August 2026
CardiologyAficamten met both main goals in the ACACIA-HCM trial, modestly improving symptoms and exercise capacity in nonobstructive hypertrophic cardiomyopathy, a condition with no targeted treatment.
28 August 2026
CardiologyThe SINGLE-AF trial found apixaban or rivaroxaban cut serious events from 1.5% to 0.5% in AF patients at intermediate stroke risk, without more major bleeding.
28 August 2026
CardiologyIn the CARDIO-TTRansform trial, monthly eplontersen lowered the faulty TTR protein but did not significantly reduce heart deaths and events in amyloid cardiomyopathy over 140 weeks.
28 August 2026